All Ingredients9462745050
VitaminsPregnancy Safe
Vitamin B12 (Cobalamin)
Also known as: cobalamin, methylcobalamin, cyanocobalamin
Vitamin B12 is essential for nerve function, red blood cell formation, and DNA synthesis. Deficiency is common in vegans, the elderly, and those on metformin or proton pump inhibitors. The body can store years' worth of B12, so deficiency develops slowly.
Key Benefits
- Prevents megaloblastic anemia
- Supports nerve health and myelin formation
- Essential for DNA synthesis
- Supports energy metabolism
- May improve mood and cognitive function
Recommended Dosage
General Use
2.4 mcg daily (RDA) — supplements typically provide 500-5000 mcg
Upper Limit
No established upper limit (water-soluble, excess excreted)
Deficiency
1000-2000 mcg daily or injections
Forms & Bioavailability
Best Forms
- ✓Methylcobalamin (active form)
- ✓Adenosylcobalamin
- ✓Hydroxocobalamin (injection form)
Forms to Avoid
- ✗Cyanocobalamin at very high doses for people with kidney issues
Safety Notes
- Very safe even at high doses
- Cyanocobalamin contains trace cyanide (negligible at normal doses)
- Absorption decreases with age — sublingual or injections may be needed
- Vegans must supplement — no reliable plant sources
Drug Interactions
Consult your healthcare provider if you take any of the following:
Metformin (reduces absorption)Proton pump inhibitorsH2 blockersColchicine
Sources
- • NIH Office of Dietary Supplements
- • American Journal of Clinical Nutrition
Top Vitamin B12 (Cobalamin) Supplements
Garden of Life Vitamin B12 1000mcg
Garden of Life
sublingual·1000mcg
USP VerifiedUSDA OrganicGMP Certified
Nutricost Vitamin B12 1000mcg
Nutricost
sublingual·1000mcg
USP Verified
Jarrow Formulas Vitamin B12 1000mcg
Jarrow Formulas
tablet·1000mcg
USP VerifiedNon-GMO Project VerifiedGMP Certified
Country Life Vitamin B12 1000mcg
Country Life
sublingual·1000mcg
Non-GMO Project VerifiedGMP Certified
Not Third Party TestedProprietary Blend
Olly Vitamin B12 1000mcg
Olly
capsule·1000mcg
Not Third Party Tested